Indication |
For the treatment of peptic ulcer disease and also to help relieve
abdominal or stomach spasms or cramps due to colicky abdominal pain,
diverticulitis, and irritable bowel syndrome. |
Pharmacodynamics |
Clidinium is a synthetic anticholinergic agent which has been
shown in experimental and clinical studies to have a pronounced
antispasmodic and antisecretory effect on the gastrointestinal tract. |
Mechanism of action |
Inhibits muscarinic actions of acetylcholine at postganglionic
parasympathetic neuroeffector sites primarily by inhibiting the M1
muscarinic receptors. |
Absorption |
Not Available |
Volume of distribution |
Not Available |
Protein binding |
Not Available |
Metabolism |
Not Available |
Route of elimination |
Not Available |
Half life |
Not Available |
Clearance |
Not Available |
Toxicity |
Signs of toxicity include confusion, paralytic ileus, urinary hesitancy/retention, and blurred vision. |
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