Indication |
For treatment and management of Parkinson's disease. |
Pharmacodynamics |
Cycrimine is a central anticholenergic used in the treatment of
the symptoms of Parkinson's disease. It is a drug used to reduce levels
of acetylcholine. Acetylcholine is usually in balance with dopamine
neurotransmitters, however lower levels of dopamine are present in the
brain of patients suffering from Parkinson's disease. By lowering levels
of acetylcholine, it is thought that this balance may be restored. |
Mechanism of action |
Cycrimine binds the muscarinic acetylcholine receptor M1,
effectively inhibiting acetylcholine. This decrease in acetylcholine
restores the normal dopamine-acetylcholine balance and relieves the
symptoms of Parkinson's disease. |
Absorption |
Not Available |
Volume of distribution |
Not Available |
Protein binding |
14-21% |
Metabolism |
Not Available |
Route of elimination |
Not Available |
Half life |
Not Available |
Clearance |
Not Available |
Toxicity |
Not Available |
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