| Indication | For use in the treatment of allergic rhinitis, hay fever, and allergic skin disorders. |
| Pharmacodynamics | Diphenylpyraline is an antihistamine that prevents, but does not reverse, responses mediated by histamine alone. Diphenylpyraline antagonizes most of the pharmacological effects of histamine, including urticaria and pruritus. Also, diphenylpyraline may exhibit anticholinergic actions (as do most of the antihistamines) and may thus provide a drying effect on the nasal mucosa. |
| Mechanism of action | Antihistamines such as diphenylpyraline used in the treatment of allergy act by competing with histamine for H1-receptor sites on effector cells. This reduces the effects of histamine, leading to a temporary reduction of allergy symptoms. |
| Absorption | Well absorbed after oral administration. |
| Volume of distribution | Not Available |
| Protein binding | > 99% in human serum albumin |
| Metabolism | Hepatic |
| Route of elimination | Not Available |
| Half life | Not Available |
| Clearance | Not Available |
| Toxicity | Not Available |
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