Pharmacology Of Oxandrolone

Indication Use to promote weight gain after weight loss following extensive surgery.
Pharmacodynamics Oxandrolone is an anabolic steroids indicated as adjunctive therapy to promote weight gain after weight loss following extensive surgery, chronic infections, or severe trauma, and in some patients who without definite pathophysiologic reasons fail to gain or to maintain normal weight, to offset the protein catabolism associated with prolonged administration of corticosteroids, and for the relief of the bone pain frequently accompanying osteoporosis. Anabolic steroids are synthetic derivatives of testosterone.
Mechanism of action Oxandrolones interact with androgen receptors in target tissues.
Absorption Not Available
Volume of distribution Not Available
Protein binding Not Available
Metabolism Renal
Route of elimination Not Available
Half life 0.55 hours (1st phage), 9 hours (2nd phase)
Clearance Not Available
Toxicity The oral LD50 of oxandrolone in mice and dogs is greater than 5,000 mg/kg.