Indication |
For infections at the following sites: upper and lower respiratory
tract; skin and soft tissue; urinary tract and acute uncomplicated
gonococcal urethritis, when due to sensitive strains of the following
organisms: Gram-positive: streptococci (including S. faecalis and S. pneumoniae) and nonpenicillinase-producing staphylococci; Gram-negative: H. influenzae, N. gonorrhoeae, E. coli, P. mirabilis, Salmonellae and Shigellae. |
Pharmacodynamics |
Bacampicillin is a prodrug of ampicillin and is microbiologically inactive. |
Mechanism of action |
During absorption from the gastrointestinal tract, bacampicillin
is hydrolyzed by esterases present in the intestinal wall. It is
microbiologically active as ampicillin, and exerts a bactericidal action
through the inhibition of the biosynthesis of cell wall mucopeptides. |
Absorption |
Absorbed following oral administration. |
Volume of distribution |
Not Available |
Protein binding |
Not Available |
Metabolism |
Not Available |
Route of elimination |
Not Available |
Half life |
Not Available |
Clearance |
Not Available |
Toxicity |
Not Available |
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