| Indication | Not Available |
| Pharmacodynamics | Bufotenin is a tryptamine related to the neurotransmitter serotonin. |
| Mechanism of action | Not Available |
| Absorption | Rapidly absorbed following intravenous administration. |
| Volume of distribution | Not Available |
| Protein binding | Not Available |
| Metabolism | Orally administered bufotenine undergoes extensive first-pass metabolism by the enzyme monoamine oxidase. |
| Route of elimination | Not Available |
| Half life | Not Available |
| Clearance | Not Available |
| Toxicity | Ingestion of Bufo toad venom and eggs by humans has resulted in several reported cases of poisoning, some of which resulted in death. The acute toxicity of bufotenin in rodents has been calculated to have an LD50 of between 200 and 300 mg/kg, which by comparison, is comparable to the LD50 for intravenous morphine (200-300 mg/kg) in mice. Death occurs by respiratory arrest. |
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